Prof David Lee
BSc (Hons), MA, PhD

 

All Publications

Page 3 of 5

    2006

    • Knight MM, Toyoda T, Lee DA and Bader DL (2006). Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose. J Biomech vol. 39 (8), 1547-1551.  
      01-01-2006
    • Chowdhury TT, Raveenthiran SP, Bader DL and Lee DA (2006). P140 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN FRAGMENT INDUCED UPREGULATION OF NITRIC OXIDE. Osteoarthritis and Cartilage, Elsevier vol. 14 
      01-01-2006
    • Lee DA (2006). Products: Spinal implant looks good so far. Biomedical Materials (JUNE), 4-5.  
      01-01-2006
    • Lee DA (2006). Spinal implants: CryoLife's spinal disc repair study completes enrolment. Biomedical Materials (SEP.), 9-10.  
      01-01-2006

    2005

    • Yeats C, Maibaum M, Marsden R, Dibley M, Lee D, Addou S and Orengo CA (2005). Gene3D: modelling protein structure, function and evolution. Nucleic Acids Research, Oxford University Press (Oup) vol. 34 (suppl_1), d281-d284.  
      28-12-2005
    • Pingguan-Murphy B, Lee DA, Bader DL and Knight MM (2005). Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles. Arch Biochem Biophys vol. 444 (1), 45-51.  
      01-12-2005
    • Screen HRC, Bader DL, Shelton JC and Lee DA (2005). Cyclic mechanical conditioning of isolated tendon fascicles results in an upregulation of collagen production. Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 193-194.  
      01-12-2005
    • Chowdhury TT, Bader DL and Lee DA (2005). Dynamic compression counteracts IL-1-induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 251-252.  
      01-12-2005
    • Wang MJ, Heywood HK, Bader DL, Paine MD, Stark JPW and Lee DA (2005). Identification and characterization of deposited fibronectin on biocompatible materials: Comparison of electrospray and wetting methods. Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 439-440.  
      01-12-2005
    • Chowdhury TT, Appleby RN, Salter DA, Bader DL and Lee DA (2005). Integrin mediated mechanotransduction in IL-1 stimulated bovine chondrocytes cultured in agarose constructs. Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 545-546.  
      01-12-2005
    • Bader DL and Lee DA (2005). Mechanical conditioning of cell-seeded constructs for soft tissue repair - Are optimisation strategies possible? 
      01-12-2005
    • Screen HRC, Shelton JC, Bader DL and Lee DA (2005). Cyclic tensile strain upregulates collagen synthesis in isolated tendon fascicles. Biochem Biophys Res Commun vol. 336 (2), 424-429.  
      21-10-2005
    • Sengers BG, Heywood HK, Lee DA, Oomens CWJ and Bader DL (2005). Nutrient utilization by bovine articular chondrocytes: a combined experimental and theoretical approach. J Biomech Eng vol. 127 (5), 758-766.  
      01-10-2005
    • Screen HRC, Shelton JC, Chhaya VH, Kayser MV, Bader DL and Lee DA (2005). The influence of noncollagenous matrix components on the micromechanical environment of tendon fascicles. Ann Biomed Eng vol. 33 (8), 1090-1099.  
      01-08-2005
    • Chowdhury TT, Bader DL and Lee DA (2005). Dynamic compression counteracts IL-1β induced INOS and COX-2 activity by human chondrocytes cultured in agarose constructs. European Cells and Materials vol. 10 (SUPPL.2) 
      01-07-2005
    • Catuogno C, Chowdhury TT, Bader DL and Lee DA (2005). Dynamic compression influences the biochemical response of human mesenchymal stem cells cultured in agarose constructs. European Cells and Materials vol. 10 (SUPPL.2) 
      01-07-2005
    • Campbell JJ, Lee DA and Bader DL (2005). Mechanical conditioning Influences Mesenchymal stem cell chondrogenesis. European Cells and Materials vol. 10 (SUPPL.2) 
      01-07-2005
    • Eniwumide JO, Lee DA and Bader DL (2005). Perfusion-Enhancement of molecular transport within 3D scaffolds. European Cells and Materials vol. 10 (SUPPL.2) 
      01-07-2005
    • Heywood HK, Bader DL and Lee DA (2005). Superficial and deep chondrocyte subpopulations both express the crabtree effect but exhibit differences in oxygen consumption rate. European Cells and Materials vol. 10 (SUPPL.2) 
      01-07-2005
    • Gao J, Lee D, Yang Y, Holdcroft S and Frisken BJ (2005). Self-Assembly of Surface-Charged Latex Nanoparticles: A New Route to the Creation of Continuous Channels for Ion Conduction. Macromolecules, American Chemical Society (Acs) vol. 38 (14), 5854-5856.  
      15-06-2005
    • (2005). British Society for Matrix Biology Autumn Meeting Joint with the UK Tissue & Cell Engineering Society, University of Bristol, UK. International Journal of Experimental Pathology, Wiley vol. 86 (3), a1-a56.  
      24-05-2005
    • Lee D, Grant A, Marsden RL and Orengo C (2005). Identification and distribution of protein families in 120 completed genomes using Gene3D. Proteins Structure Function and Bioinformatics, Wiley vol. 59 (3), 603-615.  
      14-03-2005
    • Goldberg AJ, Lee DA, Bader DL and Bentley G (2005). Autologous chondrocyte implantation. Culture in a TGF-beta-containing medium enhances the re-expression of a chondrocytic phenotype in passaged human chondrocytes in pellet culture. J Bone Joint Surg Br vol. 87 (1), 128-134.  
      01-01-2005
    • Wang Y-N, Bouten CVC, Lee DA and Bader DL (2005). Compression-induced damage in a muscle cell model in vitro. Proc Inst Mech Eng H vol. 219 (1), 1-12.  
      01-01-2005

    2004

    • Pearl F, Todd A, Sillitoe I, Dibley M, Redfern O, Lewis T, Bennett C, Marsden R, Grant A, Lee D, Akpor A, Maibaum M, Harrison A, Dallman T, Reeves G, Diboun I, Addou S, Lise S, Johnston C, Sillero A, Thornton J and Orengo C (2004). The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis. Nucleic Acids Research, Oxford University Press (Oup) vol. 33 (suppl_1), d247-d251.  
      17-12-2004
    • Lee DA, Randall F, Beattie G and Bentall RP (2004). Delusional discourse: An investigation comparing the spontaneous causal attributions of paranoid and non‐paranoid individuals. Psychology and Psychotherapy Theory Research and Practice, Wiley vol. 77 (4), 525-540.  
      01-12-2004
    • Bader DL, Shelton JC, Lee DA and SCREEN HRC (2004). Local Strain Measurement within Tendon. Strain vol. 40 (4), 157-163.  
      01-11-2004
    • Bryant SJ, Anseth KS, Lee DA and Bader DL (2004). Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain. J Orthop Res vol. 22 (5), 1143-1149.  
      01-09-2004
    • Chowdhury TT, Salter DM, Bader DL and Lee DA (2004). Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes. Biochem Biophys Res Commun vol. 318 (4), 873-881.  
      11-06-2004
    • Lee D (2004). Debt crisis looms [10]. Professional Engineering vol. 17 (8) 
      28-04-2004
    • Kim B-C, van Gelder H, Kim TA, Lee H-J, Baik KG, Chun HH, Lee DA, Choi KS and Kim S-J (2004). Activin Receptor-like Kinase-7 Induces Apoptosis through Activation of MAPKs in a Smad3-dependent Mechanism in Hepatoma Cells*. Journal of Biological Chemistry, Elsevier vol. 279 (27), 28458-28465.  
      23-04-2004
    • Bryant SJ, Chowdhury TT, Lee DA, Bader DL and Anseth KS (2004). Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels. Ann Biomed Eng vol. 32 (3), 407-417.  
      01-03-2004
    • Screen HRC, Lee DA, Bader DL and Shelton JC (2004). An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties. Proc Inst Mech Eng H vol. 218 (2), 109-119.  
      01-01-2004
    • Heywood HK, Sembi PK, Lee DA and Bader DL (2004). Cellular utilization determines viability and matrix distribution profiles in chondrocyte-seeded alginate constructs. Tissue Eng vol. 10 (9-10), 1467-1479.  
      01-01-2004
    • LEE DA, van Osch G, Verhaar JAN, Mandl EW, van der Linden JC, van der Breevaart Bravenboer J and Weinans H (2004). Extracellular matrix influences the response of chondrocytes to dynamic compression. Trans. Orthop.Rev. Soc vol. 29, 839-839.  
      01-01-2004
    • Lee DA, Fefeu S, Edo‐Ukeh AA, Orengo CA and Slingsby C (2004). EyeSite: a semi‐automated database of protein families in the eye. Nucleic Acids Research, Oxford University Press (Oup) vol. 32 (suppl_1), d148-d152.  
      01-01-2004
    • Bader DL, KNIGHT MM, Bentley G, Kayser M and Holloway I (2004). Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage. Osteoarthritis Cartilage vol. 12 (1), 17-24.  
      01-01-2004
    • Holloway I, Kayser M, Lee DA, Bader DL, Bentley G and Knight MM (2004). Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage. Osteoarthritis Cartilage vol. 12 (1), 17-24.  
      01-01-2004
    • Lee DA and Knight MM (2004). Mechanical loading of chondrocytes embedded in 3D constructs: in vitro methods for assessment of morphological and metabolic response to compressive strain. Methods Mol Med vol. 100, 307-324.  
      01-01-2004
    • Wiseman M, Bader DL, Reisler T and Lee DA (2004). Passage in monolayer influences the response of chondrocytes to dynamic compression. Biorheology vol. 41 (3-4), 283-298.  
      01-01-2004
    • Grant A, Lee D and Orengo C (2004). Progress towards mapping the universe of protein folds. Genome Biology, Springer Nature vol. 5 (5) 
      01-01-2004

    2003

    • Chowdhury TT, Bader DL and Lee DA (2003). Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs. Osteoarthritis Cartilage vol. 11 (9), 688-696.  
      01-09-2003
    • Chowdhury TT, Bader DL, Shelton JC and Lee DA (2003). Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression. Arch Biochem Biophys vol. 417 (1), 105-111.  
      01-09-2003
    • Berry CC, Shelton JC, Bader DL and Lee DA (2003). Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels. Tissue Eng vol. 9 (4), 613-624.  
      01-08-2003
    • Wiseman M, Henson F, Lee DA and Bader DL (2003). Dynamic compressive strain inhibits nitric oxide synthesis by equine chondrocytes isolated from different areas of the cartilage surface. Equine Vet J vol. 35 (5), 451-456.  
      01-07-2003
    • Lee D, Grant A, Buchan D and Orengo C (2003). A structural perspective on genome evolution. Current Opinion in Structural Biology, Elsevier vol. 13 (3), 359-369.  
      01-06-2003
    • Knight MM, Roberts SR, Lee DA and Bader DL (2003). Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death. Am J Physiol Cell Physiol vol. 284 (4), C1083-C1089.  
      01-04-2003
    • Lee DA, Reisler T and Bader DL (2003). Expansion of chondrocytes for tissue engineering in alginate beads enhances chondrocytic phenotype compared to conventional monolayer techniques. Acta Orthop Scand vol. 74 (1), 6-15.  
      01-02-2003
    • Chowdhury TT, LEE DA, Salter DM, Shelton JC and Bader DL (2003). alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta-stimulated human chondrocyte / agarose constructs and subjected to dynamic compression. Osteoarthritis Cartilage vol. 11 (Suppl 1), S2-S3.  
      01-01-2003
    • Chowdhury TT, Shelton JC, Bader DL and LEE DA (2003). Control of mechanotrasduction processes in dynamically stimulated human and bovine chondrocytes cultured in agarose constructs. Internat. J. Artificial Organs vol. 26 (9), 858-858.  
      01-01-2003

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